The GLP-1
Blueprint Guide
Daily pills are changing the GLP-1 landscape. This guide gives you the complete clinical picture — from how oral GLP-1s work to which patients they're best suited for and what's coming next in the pipeline.
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FlowWell Clinical Series
The GLP-1 Blueprint Guide
This guide is for you if…
Currently on injectable GLP-1s and curious about switching to pills
Needle-anxious patients who've been avoiding GLP-1 therapy
Interested in oral GLP-1 options like Foundayo™ or orforglipron
Healthcare providers advising patients on oral vs. injectable GLP-1 therapy
What's inside the guide
- 1 From Injections to Pills — How oral GLP-1 small-molecule drugs (orforglipron, danuglipron) differ from peptide-based injectables like semaglutide and tirzepatide
- 2 Clinical Trial Data — What the Phase 3 ATTAIN and ACHIEVE trials showed on weight loss, tolerability, and cardiovascular outcomes
- 3 Side-by-Side Comparison — Oral vs. injectable GLP-1s on cost, convenience, efficacy, side effect profiles, and who each is best suited for
- 4 The Foundayo™ Breakdown — Full profile of the first approved oral GLP-1 pill: dosing, titration schedule, and real-world patient data
- 5 Pipeline & What's Coming — Drugs in Phase 2 and 3 trials, expected approval windows through 2028, and what they could mean for patients
- 6 Patient Selection Framework — How to evaluate whether an oral GLP-1 is right for your situation, with a provider conversation guide
- 7 Side Effect Management — Common oral GLP-1 side effects, how they compare to injectable side effects, and proven management strategies
- 8 Adherence & Lifestyle Integration — Practical tips for building a daily pill routine that sticks, including timing, food interactions, and travel
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Instant PDF download. Evidence-based. Written in plain language for patients and providers navigating the shift to oral GLP-1 therapy.
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